Cellular Imaging Core

Quicklinks

Interested in using the CIC? Prerequisite: Training is required for all investigators prior to first time usage of any specific equipment in our facility. Please fill out a Service Request Form (see above). Individual equipment tabs (below) provide further detail and pricing information.

Overview

The Cellular Imaging Core is comprised of Microscopy and Image Analysis. The Core continuously explores new technologies and has invested heavily in new equipment and image analysis software. We are committed to maintaining this core as a central resource for neuroscience research at CHB and Harvard Medical School.

Recent progress in studying developmental neurobiology and neurodevelopmental disorders is enabled by increasingly sophisticated methods to visualize tissue/cellular structure/neuronal circuits and by the option to monitor real-time molecular interactions and biochemical reactions. Current advancement has been improved by access to specific antibodies for immunostaining, cloning of nucleic acids and in situ hybridization, new dyes, and cell labeling techniques. Furthermore, new microscopy techniques push against the boundaries of light physics. The CIC contains imaging technologies such as laser scanning confocal microscopy, multiphoton microscopy, fluorescence recovery after photobleaching (FRAP), fluorescence resonance energy transfer (FRET), lightsheet microscopy, and widefield fluorescence microscopy, as well as software solutions for image analysis. Core staff is dedicated to training, education, and consultation, and offers unique services in image analysis and small animal surgery. Contact us for more details or to get started.

Cite the Core

If you specifically used the Zeiss 710 at the Cellular Imaging Core, please cite the core in the following way:
We thank the IDDRC Cellular Imaging Core, funded by NIH P50 HD105351 and S10OD016453.

For use of any other instrument (except the Zeiss 710), please cite the Cellular Imaging Core in your publications in the following way:
We thank the IDDRC Cellular Imaging Core, funded by NIH P50 HD105351.

Contact Us

Core Director
Hisashi Umemori, MD, PhD
Email >

Assistant Director
Harry C. Cramer III, PhD
Email >

2 photon Manager
Cheng-Hao Chien, PhD
Email >

Microscopy & Software Core Services/Fees

Instrument IDDRC BCH External Academic Instrument Details
Zeiss LSM 700 $17/25 $19/27 $41/61 Learn More >
Zeiss LSM 980 $45 $51 $71 Learn More >
Leica SP8 STED 1x $45 $51 $71 Learn More >

*Off peak hours: M-F 7PM-9AM & Saturday & Sunday

Instrument IDDRC BCH External Academic Instrument Details
Olympus MPE-RS $59 $64
Contact the Core for more information
Learn More >

*Off peak hours: M-F 7PM-9AM & Saturday & Sunday

Instrument IDDRC BCH External Academic Instrument Details
Leica SP8 STED 1x $45 $51 $ 71 Learn More >

Instrument IDDRC BCH External Academic Instrument Details
Nikon Ti-Eclipse $11 $12 $22 Learn More >
Nikon 80i $7 $7 $9 Learn More >
Zeiss Axio Imager Z.2 $9 $11 $13 Learn More >
Instrument IDDRC BCH External Academic Instrument Details
Zeiss Lightsheet 7 $50 $55 $75 Learn More >

Instrument IDDRC BCH External Academic Instrument Details
Imaris Workstation $5 $6 $7 Learn More >

Instrument IDDRC BCH External Academic Instrument Details
CLARITY Clearing Station Contact the core for more information Learn More >
Zeiss StereoDiscovery (dissection) $6 $7 $10 Learn More >

All fees are on a per hour basis

Instrument Page >