Patient-Based Preclinical Services
Biorepository Unit >
- Consenting
- Specimen procurement
- Access to specimens
- Access to clinical data
Human Neuron Unit >
- iPSC differentiation
- Neuronal Phenotyping
- Assay development
- Screening
Clinical Phenotyping Services
Neurobehavioral Unit >
- Participants assessment
- Consultation on Methods
- Grant Consultation
- New Test development
- Electroencephalogram (EEG)
- Event related potential (ERP)
- Transcranial magnetic stimulation (TMS)
Clinical Trial / Regulatory Services
Clinical Trial & Regulatory Unit >
- Clinical study services
- Protocols/consents
- IRB application
- Research Participant Registry
- Biostatistical Services
Getting Started
- Select a service of interest and go to the Unit’s webpage.
2. Send an email to the contact person for the Unit of interest.
3. Complete the Unit’s service request form.
4. Returning users may proceed directly to iLab.
Cite the Core
Please cite the Clinical Translational Core in your publications in the following way:
We thank the IDDRC Clinical Translational Core, funded by NIH P50 HD105351.
Overview
The IDDRC Clinical Translational Core (CTC) provides resources and technical assistance to researchers throughout the pipeline from target identification to clinical trial. Preclinical services include a Human Neuron Unit for disease modeling using human neurons, and a Biorepository for management of biological samples. Clinical Phenotyping Services include the Neurobehavioral Unit and the Biomarker Unit. Services to support clinical trials include units for Regulatory guidance, a Research Participation Registry, and a Biostatics Unit.
The Clinical Translational Core objectives:
- To accelerate the translation of basic research discoveries into new cures or biomarkers for pediatric nervous system disorders.
- To develop effective new strategies for disease prevention and treatment through collaborations among Boston Children’s Hospital’s basic and clinical scientists in partnership with the IDDRC Cores and the external research community, especially other IDDRCs.
- To train future leaders of pediatric translational neuroscience.
Events organized by CT core
- Kleefstra Syndrome Family and Scientific Virtual Meeting to be held on the 4th February 2021. For more information and registration visit https://iddrc.org/news/
- Translational Neuroscience Center and CT core present a monthly seminar series from
the leaders in translational neuroscience https://iddrc.org/seminars/ - Introduction to Drug Discovery for Neuroscientists lecture course – completed. Fall of 2020 series featured experts in drug discovery from Biogen, DeepCure, Merk, Takeda, and Novartis. Stay tuned for an update about the next cycle of lectures.
- News Archive
Leadership
Core Director
Mustafa Sahin MD, PhD
Executive Director, Rosamund Stone Zander Translational Neuroscience Center
Kira Dies, ScM, CGC
Director, Clinical Research Operations
Stephanie Jo Brewster, MS
Director, Translational In Vitro Models
Elizabeth Buttermore, PhD
Director, Translational Genomic Medicine
Maya Chopra, MD, FRACP