Total Successful Projects 2016-2021

Citations:

• Prescott SL,Umanas BD, Williams EK, Burst RD, Liberles SD. “An airway protection program revealed by sweeping genetic control of vagal afferents,”
  Cell (2020), Apr 2;S0092-8674(20)30266-X. doi: 10.1016/j.cell.2020.03.004. Online ahead of print.
• McNair LF, Andersen JV, Nissen JD, Sun Y, Fischer KD, Hodgson NW, Du M, Aoki CJ, Waagepetersen HS, Rosenberg PA, Aldana BI. Conditional Knockout of GLT-1 in Neurons Leads to Alterations in Aspartate Homeostasis and Synaptic Mitochondrial Metabolism in Striatum and Hippocampus.
  Neurochem Res. 2020 [Epub ahead of print]. Cores C, D, E, and F. 
• Thuronyi BW, Koblan LW, Levy JM, Yeh WH, Zheng C, Newby GA, Wilson C, Bhaumik M, Shubina-Oleinik O, Holt JR, Liu DR. Continuous evolution of base editors with expanded target compatibility and improved activity.
  Nat Biotechnol 2019;37(9):1070-9. PMCID: PMC6728210.
• Whitman MC, Andrews C, Chan WM, Tischfield MA, Stasheff SF, Brancati F, Ortiz-Gonzalez X, Nuovo S, Garaci F, MacKinnon SE, Hunter DG, Grant PE, Engle EC. Two unique TUBB3 mutations cause both CFEOM3 and malformations of cortical development.
  Am J Med Genet A 2016;170(2):297-305. PMCID: PMC4770801. Cores E and F.
• Andzelm MM, Cherry TJ, Harmin DA, Boeke AC, Lee C, Hemberg M, Pawlyk B, Malik AN, Flavell SW, Sandberg MA, Raviola E, Greenberg ME. MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers.
  Neuron 2015;86(1):247-63. PMCID: PMC4393375. Core E.
• Latremoliere A, Latini A, Andrews N, Cronin SJ, Fujita M, Gorska K, Hovius R, Romero C, Chuaiphichai S, Painter M, Miracca G, Babaniyi O, Remor AP, Duong K, Riva P, Barrett LB, Ferreiros N, Naylor A, Penninger JM, Tegeder I, Zhong J, Blagg J, Channon KM, Johnsson K, Costigan M, Woolf CJ. Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway. Neuron 2015;86(6):1393-406. PMCID: PMC4485422. Cores C, D, and E.
  Mandel-Brehm C, Salogiannis J, Dhamne SC, Rotenberg A, Greenberg ME. Seizure-like activity in a juvenile Angelman syndrome mouse model is attenuated by reducing Arc expression.
  Proc Natl Acad Sci U S A 2015;112(16):5129-34. PMCID: PMC4413330. Core E.
• Nie D, Chen Z, Ebrahimi-Fakhari D, Di Nardo A, Julich K, Robson VK, Cheng YC, Woolf CJ, Heiman M, Sahin M. The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex.
  J Neurosci 2015;35(30):10762-72. PMCID: PMC4518051. Cores C and E.
• Niziolek PJ, MacDonald BT, Kedlaya R, Zhang M, Bellido T, He X, Warman ML, Robling AG. High-bone-mass causing mutant LRP5 receptors are resistant to endogenous inhibitors in vivo.
  J Bone Miner Res 2015;30(10):1822-30. PMCID: PMC4580530. Cores A and E.
• Talbot S, Abdulnour RE, Burkett PR, Lee S, Cronin SJ, Pascal MA, Laedermann C, Foster SL, Tran JV, Lai N, Chiu IM, Ghasemlou N, DiBiase M, Roberson D, Von Hehn C, Agac B, Haworth O, Seki H, Penninger JM, Kuchroo VK, Bean BP, Levy BD, Woolf CJ. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
  Neuron 2015;87(2):341-54. PMCID: PMC4506220. Cores C, D, and E.
• Zhang Q, Lee WA, Paul DL, Ginty DD. Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types.
  Nat Neurosci 2019;22(5):828-39. PMCID: PMC6555422
• Lin, Z., Guo, H., Cao, Y., Zohrabian, S., Zhou, P., Ma, Q., VanDusen, N., Guo, Y., Zhang, J., Stevens, S. M., Liang, F., Quan, Q., van Gorp, P. R., Li, A., Dos Remedios, C., He, A., Bezzerides, V. J. & Pu, W. T. Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth. Dev.
  Cell 39, 466–479 (2016).
• Zhou, P., Gu, F., Zhang, L., Akerberg, B. N., Ma, Q., Li, K., He, A., Lin, Z., Stevens, S. M., Zhou, B. & Pu, W. T. Mapping cell type-specific transcriptional enhancers using high affinity, lineage-specific Ep300 bioChIP-seq.
  Elife 6, (2017).
• Akerberg, B. N., Gu, F., VanDusen, N. J., Zhang, X., Dong, R., Li, K., Zhang, B., Zhou, B., Sethi, I., Ma, Q., Wasson, L., Wen, T., Liu, J., Dong, K., Conlon, F. L., Zhou, J., Yuan, G.-C., Zhou, P. & Pu, W. T. A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers.
  Nat. Commun. 10, 4907 (2019).
• He, A., Gu, F., Hu, Y., Ma, Q., Yi Ye, L., Akiyama, J. A., Visel, A., Pennacchio, L. A. & Pu, W. T. Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease.
  Nat. Commun. 5, 4907 (2014).