Quicklinks
RETURNING USERS
Proceed to iLab Login.
NEW USERS Orientation is required for all investigators prior to first time usage of equipment in our facility. Please email the Assistant Director and complete a Service Request Form (see links above).
Overview
Genetic Analysis and Editing Core (GAEC) aims to explore the genetic basis for the normal development of the nervous system, identify those mutations that affect this development to produce intellectual developmental disorders, and use this information to model the diseases to understand their pathophysiology, and test potential biomarkers and therapeutic interventions.
To support state-of-the art research, the GAEC provides IDD investigators cost-effective, rapid and efficient access to the latest technological advances both in genetic analysis and in mouse model creation through gene editing for:
-
- Sequencing DNA at all scales
- Developing gene editing strategies for cellular and animal models of human neurodevelopmental disease
- Quantitatively analyzing gene expression in normal and diseased cells and tissues.
Services
The GAG offers Sanger sequencing to validate plasmid constructs, sequence PCR products and for all molecular experiments requiring DNA sequencing, and a full suite of assays and tools for genomic-level analysis.
Services
- Nucleic Acid Sample Preparation & Quality Control
- Genotyping
- Sequencing
- RNA Expression Quantification
Gene Editing
The GEG works with investigators to create genetically engineered mouse models. Our goal is to offer expert advice and technical expertise in an easily accessible, affordable and efficient manner.
Services
- Gene editing
- Gene targeting
- Transgenic
- Cryopreservation
- Re-derivation