Image Analysis

The Core offers a number of software systems for quantitative morphometry of complex neuronal and glial structures. Dr. Innocent is available to assist with optimization of the software programs for these specific tasks. Software in the core includes:

  • Metamorph
  • Volocity Visualization, Quantitation and Restoration
  • Imaris

This component provides capabilities for:

  • 2-D and 3-D reconstruction and visualization of cellular structure and morphology:
  • 3D anatomical brain mapping
  • Serial section reconstruction
  • Accurate quantification of cell number and objects using unbiased stereology
  • Deconvolution
  • Co-localization
  • Movement tracking
  • Three-dimensional quantitative volume rendering from either serial light or electron micrographs or from laser scanning confocal microscope images
  • Interactive and automated filament tracing
  • Custom-digital analysis with capabilities to write macros that interact with the software systems